by Dr. Yashashwini Reddy | Aug 27, 2025
Validation of Clean Room Pass Boxes 1. Introduction A pass box is an enclosed space with doors on both sides, installed between two areas of different cleanliness grades.It allows the transfer of materials with minimum air turbulence and controlled contamination...
by Dr. Yashashwini Reddy | Aug 27, 2025
Principle and Working of Autoclave 1. Principle The autoclave works on the principle of moist heat sterilization using saturated steam under pressure. When pressure is applied to water, its boiling point increases. At 121 °C (15 psi / 1.05 kg/cm² above atmospheric...
by Dr. Yashashwini Reddy | Aug 27, 2025
Validation of Fumigation in Cleanroom Area Fumigation in pharmaceutical cleanrooms is an essential process to control microbial contamination and maintain aseptic conditions. It involves the use of chemical agents (commonly formaldehyde, hydrogen peroxide vapor, or...
by Dr. Yashashwini Reddy | Aug 27, 2025
Importance of Microbiological Analysis in Cleaning Method Validation Cleaning Method Validation (CMV) is a critical component in pharmaceutical manufacturing to ensure that equipment is free from product residues, cleaning agents, and microbial contaminants before...
by Dr. Yashashwini Reddy | Apr 15, 2025
Vaccine production utilizes several types of filling equipment, primarily liquid filling machines and powder filling machines. These machines are crucial for accurately and efficiently filling vials, syringes, or other containers with the vaccine formulation, ensuring...
