by Dr. Yashashwini Reddy | Sep 1, 2025
🌡️ Different Types of Temperature Sensors 1. Thermocouples Principle: Seebeck effect (voltage generated at junction of two dissimilar metals). Range: –200 °C to +1800 °C (depending on type: J, K, T, R, S). Pros: Wide range, rugged, fast response. Cons: Lower accuracy...
by Dr. Yashashwini Reddy | Sep 1, 2025
🧪 Qualification Procedure for Vial Washing Machine A Vial Washing Machine is a critical equipment in sterile manufacturing, ensuring removal of particulate and microbial contamination before sterilization and filling. Its qualification ensures consistent performance...
by Dr. Yashashwini Reddy | Sep 1, 2025
🧪 Validation of Clean Room Pass Boxes 📌 What is a Pass Box? A Pass Box is an enclosure fitted between two cleanroom areas or between a cleanroom and a non-cleanroom. It allows transfer of materials while minimizing cross-contamination and maintaining cleanroom...
by Dr. Yashashwini Reddy | Sep 1, 2025
🧼 Cleaning Validation of CIP Systems in Pharmaceuticals 🔹 What is CIP? Clean-in-Place (CIP) is an automated method for cleaning process equipment (bioreactors, fermenters, tanks, piping, filling lines) without disassembly. Ensures removal of residues (API, excipients,...
by Dr. Yashashwini Reddy | Aug 29, 2025
1. Purpose To establish a procedure for environmental monitoring of the manufacturing area to ensure controlled conditions and compliance with cGMP requirements. 2. Scope This SOP applies to all classified manufacturing areas (Grade A, B, C, and D) where sterile or...
