by Dr. Yashashwini Reddy | Sep 2, 2025
1. Influence on Stability Moisture Sensitivity: Smaller granules have a larger surface area, which can increase moisture absorption, leading to hydrolytic degradation of moisture-sensitive drugs. Oxidation: Increased surface area also accelerates oxidative...
by Dr. Yashashwini Reddy | Sep 2, 2025
Spillage Management in Pharmaceutical Production Area Spillages in pharmaceutical production areas can pose serious risks including contamination, product quality compromise, safety hazards, and regulatory non-compliance. Effective spillage management ensures product...
by Dr. Yashashwini Reddy | Sep 2, 2025
📌 Restricted Access Barrier System (RABS) in Pharmaceuticals A Restricted Access Barrier System (RABS) is an advanced containment and protection technology used in pharmaceutical sterile manufacturing to reduce contamination risks. It provides a physical and...
by Dr. Yashashwini Reddy | Aug 30, 2025
Standard Operating Procedure (SOP) for Cleaning of Deep Freezer 1.0 Purpose To define the procedure for cleaning and maintaining the deep freezer to ensure proper functioning, prevent contamination, and maintain sample integrity. 2.0 Scope This SOP applies to all deep...
by Dr. Yashashwini Reddy | Aug 27, 2025
Maintenance of Aseptic Conditions in Pharmaceutical Sterile Areas 1. Introduction Sterile areas in pharmaceutical manufacturing (e.g., aseptic filling, compounding, cleanrooms, isolators) require strict control to prevent contamination. Maintaining aseptic conditions...
