by Dr. Yashashwini Reddy | Aug 9, 2025
Different Types of HPLC Detectors 1. UV/Vis Absorbance Detector Principle: Measures absorbance of analytes at a specific wavelength (Beer-Lambert Law). Types: Fixed Wavelength UV (e.g., 254 nm) Variable Wavelength UV Diode Array Detector (DAD/PDA) – allows spectral...
by Dr. Yashashwini Reddy | May 1, 2025
Validation and Calibration of Melting Point Instruments Introduction The melting point of a substance is a critical physical property used to identify and characterize chemicals, particularly in the pharmaceutical and chemical industries. For accurate and reproducible...
by Dr. Yashashwini Reddy | May 1, 2025
The calibration of automatic potentiometric titrators ensures the accuracy and reliability of titration results. This process involves verifying and adjusting the performance of the electrode system, burette system, and software against known standards. Below is a...
by Dr. Yashashwini Reddy | Apr 29, 2025
System suitability in High-Performance Liquid Chromatography (HPLC) analysis is a set of tests conducted to ensure that the HPLC system is performing optimally for the specific analysis being performed. These checks help determine if the system is capable of producing...
by Dr. Yashashwini Reddy | Apr 29, 2025
The paddle and basket dissolution apparatus are both used in pharmaceutical testing to determine the rate at which a drug dissolves in a specific solution, typically simulating conditions in the human digestive system. However, they operate differently and are used...
