by Dr. Yashashwini Reddy | Aug 27, 2025
Principle and Working of Autoclave 1. Principle The autoclave works on the principle of moist heat sterilization using saturated steam under pressure. When pressure is applied to water, its boiling point increases. At 121 °C (15 psi / 1.05 kg/cm² above atmospheric...
by Dr. Yashashwini Reddy | Sep 14, 2024
Autoclave Sterilization: It is one of the critical processes done in the pharmaceutical and medical fields, today in this article we will discuss why 121 degrees Celsius is used as the standard temperature with a clear explanation. Sterilization at 121°C is...