by Dr. Yashashwini Reddy | Apr 17, 2025
1. What is LCMS and how does it work? Explanation: This is a foundational question. LCMS combines liquid chromatography (LC) for separating compounds and mass spectrometry (MS) for detecting and identifying them based on mass-to-charge ratio (m/z). It is widely used...
by Dr. Yashashwini Reddy | Apr 16, 2025
1. What are the different types of HPLC columns? Reversed-phase columns: These are the most commonly used, where the stationary phase is nonpolar (e.g., C18). Polar compounds are retained longer. Normal-phase columns: The stationary phase is polar, while the mobile...
by Dr. Yashashwini Reddy | Nov 4, 2024
Top HPLC Interview Questions and Answers for Freshers and Experienced Candidates High-Performance Liquid Chromatography (HPLC) is a vital analytical tool in the pharmaceutical industry, helping to identify, separate, and quantify compounds. Here’s a detailed guide...