by Dr. Yashashwini Reddy | Aug 11, 2025
Calibration of Karl Fischer Apparatus 1. Introduction The Karl Fischer (KF) apparatus is used for accurate determination of water content in samples. Calibration ensures the instrument delivers precise and reproducible results, meeting pharmaceutical and regulatory...
by Dr. Yashashwini Reddy | May 1, 2025
Optimization and Standardization of Karl Fischer Titration Equipment Karl Fischer (KF) titration is a widely used technique for determining the water content in various substances, such as chemicals, pharmaceuticals, foods, and oils. The accuracy and precision of this...
by Dr. Yashashwini Reddy | Apr 22, 2025
Standard Operating Procedure (SOP) Here is a Standard Operating Procedure (SOP) for performing Performance Checks on a Karl Fischer Apparatus used for moisture determination: 1. Purpose To describe the procedure for...
by Dr. Yashashwini Reddy | Apr 19, 2025
1. What is Karl Fischer titration? Karl Fischer titration is an analytical technique used to determine water content in a wide range of substances. It is based on the chemical reaction between iodine and water in the presence of sulfur dioxide and a base, typically in...
by Dr. Yashashwini Reddy | Sep 6, 2024
“Standard Operating Procedure for Operating and Calibration of Karl Fischer Apparatus for Moisture Content Determination” 1.0 OBJECTIVE To define the procedure for the operation of the Karl Fischer apparatus used to determine moisture content in samples....
