by Dr. Yashashwini Reddy | Sep 2, 2025
1. Influence on Stability Moisture Sensitivity: Smaller granules have a larger surface area, which can increase moisture absorption, leading to hydrolytic degradation of moisture-sensitive drugs. Oxidation: Increased surface area also accelerates oxidative...
by Dr. Yashashwini Reddy | May 3, 2025
Granule size plays a crucial role in the formulation and performance of tablet-based pharmaceutical products. It significantly affects both the stability of the tablet during its shelf life and the bioavailability of the drug when taken by the patient....