“Understanding Capsule Sizes: Capacities and Volumes in Pharmaceutical Applications”
Capsule Sizes, Fill Capacities, and Volumes
Capsules are a popular dosage form in pharmaceuticals, known for their convenience and effectiveness. They come in various sizes, determining how much material they can hold. Below is a detailed overview of common capsule sizes, their respective fill capacities, and fill volumes:
- Size 000
- Fill Capacity: 800-1600 mg
- Fill Volume: Approximately 1.37 mL
- Length: 26-28 mm
- Size 00
- Fill Capacity: 600-1100 mg
- Fill Volume: Approximately 0.95 mL
- Length: 23-25 mm
- Size 0
- Fill Capacity: 400-800 mg
- Fill Volume: Approximately 0.68 mL
- Length: 21-23 mm
- Size 1
- Fill Capacity: 300-600 mg
- Fill Volume: Approximately 0.50 mL
- Length: 19-21 mm
- Size 2
- Fill Capacity: 200-400 mg
- Fill Volume: Approximately 0.37 mL
- Length: 18-19 mm
- Size 3
- Fill Capacity: 150-300 mg
- Fill Volume: Approximately 0.30 mL
- Length: 15.5-16 mm
- Size 4
- Fill Capacity: 100-200 mg
- Fill Volume: Approximately 0.21 mL
- Length: 14-15 mm
- Size 5
- Fill Capacity: 60-130 mg
- Fill Volume: Approximately 0.13 mL
- Length: 11-12 mm
These capacities are approximate and can vary based on the density of the substance being encapsulated. The selection of the appropriate capsule size is crucial for both medication formulation and patient compliance, particularly when considering factors such as dosage requirements and ease of swallowing.
Size 000 is the largest and size 5 is the smallest capsule size.